Barbara Bush is in failing health and will not seek additional medical treatment, the Bush family spokesman announced Sunday.
Mrs. Bush, 92, has been hospitalized several times in Houston, Texas, over the past year to be treated for chronic pulmonary disease and congestive heart failure, her family has said.
Bush is the mother of former President George W. Bush, 71, the 43rd U.S. president.
Bush is also the mother of George W. Bush, who served as president from 2001 until 2009, and Jeb Bush, the former governor of Florida who ran for president in 2016.
Most recently, she was admitted to Houston Methodist Hospital on Good Friday suffering from shortness of breath.
At the time, she said she was more interested in running a household than in helping her husband run the country. In years past she has been hospitalized for Graves' disease, a thyroid condition, and bronchitis, a respiratory ailment.
Former First Lady Barbara Bush is in failing health, according to a family spokesperson. "She is surrounded by a family she adores, and appreciates the many kind messages and especially the prayers she is receiving", the statement read. Her son, the 43rd USA president, is 71.
Just this month, the former first lady wrote about her husband in a note for the spring edition of Smith College's alumnae magazine.
Bush also revealed her secret for a long life: medical attention.
Mr Bush, who served as USA president from 1989-93, suffers from a form of Parkinson's disease and uses a wheelchair.
She continued: "Also, George Bush has given me the world". They got engaged right before he left to fight in World War II as a Navy pilot.