Prosecutors also unleashed other passages from Cosby's graphic deposition, including his accounts of purported sexual encounters with Constand and how he apologized to her mother a year later for being "a dirty old man with a young girl".
Benson said prosecutors want jurors to accept "a fabricated story about three small, blue pills" and believe that they're "somehow quaaludes".
Harry Milman, the defense pharmacology and toxicology expert, said Cosby could not have given Constand Quaaludes, because they only ever came in the form of a white pill.
The Associated Press doesn't typically identify people who say they're victims of sexual assault unless they grant permission, which Constand and Dickinson have done.
The defense wants jurors to hear deposition testimony from Andrea Constand's friend, Sheri Williams.
Constand also traveled frequently during this period in her job as an operations manager for Temple University's women's basketball team.
The defense says it wanted to put Williams on the stand to show that Constand "could not have been the unwitting victim" prosecutors have portrayed.
That line of questioning was part of Cosby's hope to paint Constand a liar. The TV star wound up settling with Constand for almost $3.4 million.
Bill Cosby's defense team was dealt a serious blow Friday when the judge blocked them from presenting testimony describing his accuser as a weed-smoking, magic mushroom addict driven by a desire for fame and fortune. Travel itinerary information introduced with Harjo revealed Cosby to have been in other cities on December 23 and December 31, 2003, and January 12, 2004. She said they were in touch as she went to police in January 2005 with allegations Cosby drugged and molested her about a year earlier.
He also scolded the defense for having just one witness ready for the day - the same day the court would hear testimony from the prosecution's final witness.
The defense immediately asked Judge Steven O'Neill to acquit Cosby and send jurors home, arguing prosecutors hadn't proved aggravated indecent assault charges.
Cosby said in a subsequent police interview that he gave Constand 1 1/2 tablets of Benadryl to help her relax, then fondled her breasts and genitals.
Jurors at Cosby's first trial past year also heard excerpts from the deposition but deadlocked on sexual assault charges.
At the first trial previous year, which ended in a mistrial after the jury was deadlocked, Ms. Constand had testified to being in close contact with Ms. Williams around the period she said she was assaulted by Mr. Cosby.
Cosby paid Constand $3.38 million to settle a civil lawsuit she filed after Pennsylvania prosecutors in 2005 initially declined to charge Cosby for the alleged assault.
A prosecution drug expert is telling jurors that Bill Cosby's chief accuser could have been made woozy by either the cold and allergy medicine Benadryl or by quaaludes.
Andrea Constand says Cosby gave her three unidentified blue pills that knocked her out and then sexually assaulted her at his suburban Philadelphia home in 2004.
In a transcript read to the jury Wednesday, the "Cosby Show" star said he obtained seven prescriptions for quaaludes from his doctor in Los Angeles in the 1970s, ostensibly for a sore back, but added he didn't use them himself because they made him exhausted.
The judge in Bill Cosby's sexual assault retrial is rejecting the defense's fifth bid for a mistrial.
The jury is expected to hear more defense witnesses starting Monday morning.
Prosecutor Stewart Ryan irked Cosby's lawyers during Jackson's cross-examination by repeatedly saying they "created" her affidavit.
O'Neill said there were "simply no grounds for a mistrial" and that Cosby's lawyers were raising the issue too late. He says it was consensual.
Testimony wrapped up early on Day 10 of Cosby's retrial.
Dr. Timothy Rohrig testified Benadryl's active ingredient, diphenhydramine, can cause "mental clouding", muscle weakness and even short-term amnesia.