Erdogan called the U.S. embassy move from Tel Aviv to the disputed city of Jerusalem "very, very unfortunate" and said it "will increase tensions and ignite an even greater fire between communities".
The United States has lost its role as mediator in the Middle East, President Erdogan of Turkey told an audience in London as he outlined a "bleak picture" of an global order reminiscent of the lead-up to the Second World War.
The Turkish president announced he was calling a "giant meeting" on Friday to protest Israel's actions at the vast Yenikapi area in Istanbul, which has capacity for more than a million people.
Last week, the Israeli government said the ongoing border protests constituted a "state of war" in which global humanitarian law did not apply.
"Today will go down in the history as Bloody Monday for Muslims and Islamic countries", Bozdag said.
Erdogan also said on Monday that the eastern Mediterranean region will face a sustained security threat if Cyprus continues unilateral operations.
He also said Turkey had called for an emergency meeting of the Organization of Islamic Cooperation, to be held on Friday.
He said U.S. President Donald Trump was attempting to distract attention from domestic problems by moving the embassy, "trying to hide the fire inside by setting fires outside". "As you know, this occupation has continued since 1948", Erdoğan said.
Thousands of Palestinians gathered on the Gaza Strip's eastern border since early Monday morning to take part in protests aimed to commemorate the Nakba anniversary and protest the relocation of the U.S. Embassy from Tel Aviv to Jerusalem.