European nations are moving to protect their companies from a resumption of stiff US sanctions on firms doing business in Iran, in a critical part of their bid to keep the Iranian nuclear deal alive and ensure it continues to benefit Iran's economy.
"The Prime Minister raised the potential impact of United States sanctions on those firms which are now conducting business in Iran".
The foreign minister said the commitment of other partners to the Iran deal should be respected.
And Russian President Vladimir Putin has spoken to German Chancellor Angela Merkel and Turkey's President Recep Erdogan about how to save the 2015 agreement with Iran, according to Russia's official press agency TASS.
"We are determined to keep this deal in place", declared Federica Mogherini, an Italian politician who serves as High Representative of the European Union (EU) for Foreign Affairs and Security Policy.
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Trump pulled out of the nuclear deal, which he has previously called the "worst deal ever", on Tuesday after the fixes that he proposed in January were not agreed to by the European signatories to the deal.
"Do we want to be vassals deferring with a curtsy and a bow to decisions made by the U.S. so that the U.S. polices the world economy?"
In a phone call dominated by Iran, the Prime Minister and President agreed to hold talks between the United Kingdom and USA governments on the effect of sanctions on British companies.
Iran has supported Syria's right to defended itself against aggression from Israel, Iranian state TV has reported.
Addressing the sanctions, le Maire said he had called his United States counterpart Steven Mnuchin and asked him "about either exemptions for a number of our companies, or longer deadlines [to comply with renewed sanctions]".
"He introduced a new element, the element of leverage to a stale, non-productive reality that only encouraged the Iranians to continue their incredibly risky behaviour, particularly in Syria, by threatening Israel by surrounding it with missiles and expecting us to sit there and just wait until something happens".
There are signs, however, that other members of the Organization of the Petroleum Exporting Countries (OPEC) will raise output to counter the Iran disruption.
Oil prices have risen 14% this year, half of this increase reflects stronger global demand, a Bloomberg Economics model suggests.
"The President of the Atomic Energy Organization of Iran has been tasked with taking all necessary steps in preparation for Iran to pursue industrial-scale enrichment without any restrictions, using the results of the latest research and development of Iran's fearless nuclear scientists", the statement said.