The first edition of FIFA's proposal is due to take place in 2021 and consists of a 24-team competition held every four years, during the second half of June.
Following a meeting in Lyon, the PFSC said its members had not been properly consulted and added in a statement that it "unanimously expressed serious reservations about the process surrounding the FIFA Club World Cup and Global Nations League proposals".
The first version of the restructured tournament would take place in 2021, with China possibly in line to play host.
Federation Internationale de Football Association is reported to have already presented the project to seven of Europe's biggest clubs including Real Madrid, Barcelona and Bayern Munich.
They could be joined by Atletico Madrid, Borussia Dortmund, Paris Saint-Germain and Portuguese pair Porto and Benfica. The 24 clubs would share a pot of approximately £1.5 billion with the victor earning £100 million and a guaranteed £50 million just for participating.
The tournament would consist of 24 teams who would compete in eight groups of three, the winners of these eight groups would then progress on to the quarter-finals, which would then obviously be followed by the semi-finals and final. A consortium of backers from Saudi Arabia, the United Arab Emirates and Japan are said to have pledged the money to make the tournament happen. It is expected to replace the existing tournament - which takes place on an annual basis - and the Confederations Cup.
Bobby Barnes, the European president of worldwide players' union FIFPro, is a part of a committee that will meet in Lyon at some point today to talk about the plans.
But Jurgen Klopp's Champions League finalists are not the only Premier League club close to being asked.
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