Since early February, when Israel says it shot down an Iranian drone laden with explosives that were launched from Syria, the Israel Defense Forces have increased retaliatory strikes in Syria at Iranian targets.
"The Zionist regime's frequent attacks on Syria under fabricated and baseless excuses is a breach of the national sovereignty and territorial integrity of Syria and in defiance of all worldwide laws and regulations", Iranian Foreign Ministry spokesperson Bahram Qasem said.
"If Trump decides to take military risks in the Gulf or Syria against Iran as a effect of a more aggressive stance, then others - including Israel - can get drawn in".
"But we did say after the (Western) strikes (on Syria) that of course Russian Federation reserved the right to do anything it considered necessary".
The Syrian army said in a statement on Syrian TV: "A new Israeli aggression was confronted yesterday and our air defence system was successful in intercepting a major number of the Israeli missiles that targeted Syrian military positions". Iran, which has invested billions in ensuring Bashar al-Assad's survival, is interested in creating a balance of deterrence against Israel by building permanent bases in Syria.
In response to the raids, Moscow, which also supports Assad, called on both Israel and Iran to show restraint. We urge Iran to refrain from further actions which will only lead to increased instability in the region", said Johnson, adding: "It is crucial to avoid any further escalations, which would be in no one's interest.
"We hope we can, but there are a lot of things playing a role in this", she said.
Iran says it is ready to restart its nuclear program on an "industrial scale" in the wake of the decision by US President Donald Trump to abandon the deal that curbs the country's nuclear ambitions.
Iran has not claimed responsibility for the rocket fire.
Israeli strikes on Iranian targets in Syria have the advantage of weakening Iran vis-à-vis Russian Federation inside Syria without Moscow having to confront Tehran directly.
Israel and Iran have long fought each other through proxies, and with the new exchange each seemed to be sending a warning that a direct clash between them could swiftly escalate.
"We will not let Iran turn Syria into a forward base against Israel".
In the wake of President Trump's announcement of the USA withdrawal from the Iranian nuclear accord and the direct clashes between Israeli and Iranian forces in Syria, Israeli Prime Minister Benjamin Netanyahu went to Moscow to meet with Russian President Vladimir Putin and watch a parade.
Israel, which has vowed to prevent any entrenched Iranian military presence in southern Syria, is suspected of carrying out several rounds of strikes against Tehran-backed forces. No Israeli soldier or civilian was hurt, and there was no damage on the Israeli side. During the Obama administration, the U.S. sided mainly with Iran. At first glance, it would seem that the two events are closely tied - Iran no longer constrained by a nuclear deal, and Israel emboldened by its US ally's action.
The army described its sweeping retaliatory strike as a devastating blow to Iran's military presence on the territory of its ally.
Israel said 20 rockets, either Fajr or Grad type, were fired from Syria at its forces in the occupied Golan Heights at around midnight.
Iran's hardliners are already mobilising against any concessions to Europe, with hundreds protesting in Tehran after Friday prayers, saying it was time to abandon the deal. On April 30, Israel was said to have struck government outposts in northern Syria, killing more than a dozen pro-government fighters, many of them Iranians.
"Today, the main supporters of these groups are directly attacking and invading Syrian territories in an attempt to avenge the many failures of their self-created terrorists and tip the scales in their favor", he said.
Israel had been preparing itself for weeks for possible Iranian retaliation.