The match will also be new Arsenal manager Unai Emery's first in English football's top flight.
The Premier League season may not get underway until August 11, but Liverpool fans can begin pencilling in key dates after the fixtures were released this morning. After the Gunners host the champions, the team now managed by Emery are at Chelsea.
The pair are among six Premier League clubs in the competition, with Manchester City, Manchester United, Tottenham and Liverpool also competing.
Manchester United will be determined to catch their neighbours - who romped home to the title last term with a 100-point tally - and Jose Mourinho and co will begin that pursuit at home to Leicester.
Perhaps the most eagerly anticipated game next season will not be the Manchester derby, but the first clash between City and Liverpool at Anfield on October 6.
And 2019 faces an explosive start with Liverpool due to travel to the Etihad for what promises to be another key game in the battle for the title next season.
They will play promoted Fulham at Wembley in their first home game of the season on the weekend of 18-19 August.
Arsenal and Chelsea, who have both just had extremely disappointing seasons, will play a friendly match in Dublin. That hasn't, however, stopped the club preparing our pre-season plans.