He's now occasionally credited as Dwayne "The Rock" Johnson.
The thriller stars The Rock as a security guard for the (fictional) tallest building in the world, a swirling glass-and-steel monolith in Hong Kong.
Ten years after losing a leg in a botched hostage rescue mission, former Federal Bureau of Investigation operative Will Sawyer (Johnson) has settled down with his own security consultancy company (though we never see any of his employees), a lovely wife (Neve Campbell, who plays a surgeon but doesn't save anyone on-screen), and two young kids.
In July 2017, a "Run The Rock 2020" campaign committee was formed, though Johnson, a registered Independent, wasn't involved in its creation.
In the mid 2000s, when Dwayne "The Rock" Johnson moved from WWE wrestling into a full-time career as a Hollywood star, there was a brief period of time where Johnson dropped his wrestling moniker.
And Dwayne is keen to work alongside Skyscraper director Rawson Marshall Thurber again.
Right out of the gate the movie shows us that Will is going to be a more mellow character than we are used to Johnson playing.
After months of speculation, the actor told Vanity Fair on Tuesday that a bid for the White House in the next presidential election will not be happening.
Is the movie completely unrealistic and full of cliches and head-scratching plot points? Of course. But like "Rampage" earlier this year, you're paying your hard-earned money to see The Rock do some insane stuff, and you won't be disappointed.
OK, so it's ridiculous, but slightly ridiculous action movies are Johnson's brand (they're actually making a sequel to San Andreas), and what fans want in the context of that silliness are reasonably competent action and suspense - Johnson making incredible leaps from cranes onto burning buildings, or stabilizing a collapsing beam with his bulging muscles while imperiled innocents scurry past. "'Jumanji.' 'Rampage.' And now 'Skyscraper.' Saved the best for last".
"I reached a point in my career where I was exhausted of trying to be something I wasn't", Johnson said of switching back to the nickname.
"Skyscraper" certainly has a more serious tone than most of what Johnson and Thurber do, which might throw some audiences off.