USA streaming service Netflix said the series had access to "never-before-heard testimonies from those at the heart of the story, including friends of the McCann family, investigators working the case and from those who became the subject of media speculation and rumour".
Madeleine, 3, went missing while she and her family were on holiday in Portugal in 2007 and the United Kingdom investigation into what happened to her remains open.
A source inside the production team added: "We would have welcomed the opportunity of working with the McCanns directly but they informed us they couldn't and wouldn't consider taking part while a police investigation is into their daughter's abduction is ongoing".
As the Independent reports, McCann said at a statement: "We are aware that Netflix are planning to screen a documentary in March 2019 about Madeleine's disappearance".
However, top United Kingdom cop Jim Gamble - who was a key figure in the first British investigation in to her disappearance - believes people WILL find out what really happened to the little girl. The parents reportedly checked on the children throughout the evening until they discovered that Madeleine was missing at about 10 p.m.
It also features interviews with Goncalo Amaral, the retired Portuguese police chief who is certain that Gerry and Kate killed their daughter then staged a kidnapping to cover it up.
Their spokesperson told The Guardian: "Kate and Gerry didn't ask for it and don't see how it will help the search for Maddie on a practical level, so they chose not to engage".
An artists impression of what Madeleine McCann would look like today.
Netflix announced the documentary project in 2017.