Well, nearly everything. Max Allegri's side suffered just their third defeat of the season to Roma on Sunday in the Italian capital, with late goals from Florenzi and Edin Dzeko sealing an important three points for a side chasing Champions League qualification.
Alessandro Florenzi broke the deadlock with 11 minutes remaining before Edin Dzeko sealed the win late on.
Needing a top four finish to qualify for the Champions League, they are three points behind third-placed Atalanta and one adrift of Inter Milan, who have a game in hand.
The Old Lady were knocked out of the Champions League in the quarter-final stage by surprise package Ajax, a disappointment considering their designs on the trophy and the recruitment of the superstar Portuguese. "We have to continue to believe".
Tempers flared between the Juventus forward and Roma defender in the 58th minute of their clash at the Stadio Olimpico with Florenzi nearly squaring up close to Ronaldo. "Even if not everything depends on us, we must reach the end with a clear conscience".
AC Milan is above Roma thanks to a better head-to-head record, which is the tiebreaker in Italy.
Fabio Quagliarella pulled a goal back for Sampdoria converting a penalty in injury time to take his Serie A leading tally to 26 goals - five more than Juventus star Ronaldo.
Andrea Belotti scored twice for Torino, including a stunning overhead kick to win the match, eight minutes from time.
Napoli beat SPAL 2-1 in a game with nothing to play for as Carlo Ancelotti's side are already assured of second place and SPAL have staved off relegation.