At the half, Jacobs had just 19 rushing yards, but eventually the levies broke, and No. 28 left his imprint on the game.
Ferrell was the fourth rookie since sacks became official (1982) to have eight tackles and 2.5 sacks in a game.
"It was a special moment for this team and a special moment for my teammates", Harris told reporters.
Daniel Carlson missed the extra point, putting more pressure on the exhausted Raiders defense to stop Rivers.
If Oakland wins, they will remain in second place in the AFC West, whereas if Los Angeles wins, they will jump over the Raiders and move into second place behind the Chiefs. Los Angeles took a 14-10 edge when Melvin Gordon scored a 3-yard rushing touchdown 4:20 before halftime.
Derek Carr then executed the two-minute drill, finding fullback Alec Ingold for a nine-yard touchdown to put the Raiders back in front right before halftime. The score gave the Chargers at 17-14 advantage at the break.
The Chargers settled for a field goal after getting inside the 10 later in the quarter. Chargers kicker Mike Badgley answered with another field goal at the end of the third quarter.
Three minutes earlier, Philip Rivers threw a six-yard pass to Austin Ekeler which had given the Chargers a 24-20 lead.
It was a repeat performance from Sunday when Carr's late TD pass to Hunter Renfrow and Joseph's pass breakup in the end zone delivered a 31-24 win over Detroit. Harris totaled 115 yards on his interception returns, out-gaining every pass catcher in receiving yards and player in rushing yards.